Robert N, Posthaus H
Institute for Animal Pathology, Berne University, Switzerland.
J Wildl Dis. 1999 Jan;35(1):141-4. doi: 10.7589/0090-3558-35.1.141.
A uterine adenocarcinoma with widespread visceral implantation and lymphatic metastases is described in a 4-yr-old captive nulliparous sika deer (Cervus nippon). The tumor was histologically characterized by proliferation of irregularly shaped acini and tubules lined by single- or multi-layered pleomorphic epithelial cells, which were sometimes multinucleated and contained PAS positive mucin. The neoplastic tissue was invasive and showed a marked desmoplastic reaction. A relationship between the tumor and a hormonal imbalance could not be ruled out. This is the first report of a tumor of the reproductive tract in a cervid.
本文描述了一只4岁圈养未生育的梅花鹿（Cervus nippon）发生的子宫腺癌，伴有广泛的内脏种植和淋巴转移。肿瘤组织学特征为不规则形状的腺泡和小管增生，内衬单层或多层多形性上皮细胞，这些细胞有时多核，含有PAS阳性黏液。肿瘤组织具有侵袭性，并表现出明显的促纤维增生反应。不能排除肿瘤与激素失衡之间的关系。这是关于鹿科动物生殖道肿瘤的首次报道。
