Duncan Colleen, Powers Jenny, Davis Tracy, Spraker Terry
Colorado State University Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
J Vet Diagn Invest. 2007 Sep;19(5):560-3. doi: 10.1177/104063870701900518.
A captive, 20-year-old female elk (Cervus elaphus nelsoni) euthanized due to progressive lameness and weight loss was presented to Colorado State University Veterinary Diagnostic Laboratory for postmortem examination. Within the uterus there was a poorly demarcated, multilobulated mass measuring 10 cm in diameter. Histologically the tumor was an adenocarcinoma. Histologic examination of the ovaries revealed unilateral metastasis. A focal, 1-cm diameter adenocarcinoma was identified within the abomasum; this tumor was histologically distinct from the neoplasm found in the uterus and ovary. Although this elk had a history of experimental reproductive treatments, including leuprolide, gonadotropin-releasing hormone vaccine, and Brucella abortus vaccination, it was most likely that both tumors represent spontaneous, independent neoplastic transformations and were unrelated.
一头20岁的雌性圈养麋鹿（Cervus elaphus nelsoni）因进行性跛行和体重减轻而被安乐死，随后被送至科罗拉多州立大学兽医诊断实验室进行尸检。子宫内有一个边界不清、多叶状的肿块，直径为10厘米。组织学检查显示该肿瘤为腺癌。卵巢的组织学检查发现有单侧转移。在皱胃内发现一个直径1厘米的局灶性腺癌；该肿瘤在组织学上与子宫和卵巢中的肿瘤不同。尽管这头麋鹿有过包括亮丙瑞林、促性腺激素释放激素疫苗和布鲁氏菌流产疫苗在内的实验性生殖治疗史，但这两个肿瘤很可能均代表自发的、独立的肿瘤性转化，且彼此无关。
