Dymond K E, Fewell J E
Department of Physiology & Biophysics, The University of Calgary, Health Sciences Centre, Alberta, Canada.
Physiol Behav. 1999;65(4-5):889-92. doi: 10.1016/s0031-9384(98)00198-x.
The induction of psychological stress is often accompanied by a transient increase in core temperature, commonly referred to as stress induced hyperthermia. Although stress-induced hyperthermia occurs when rats, mice, and pigs are exposed to a novel stimulus (e.g., a simulated open field, restraint, etc.), whether or not it occurs in guinea pigs has not been investigated. The present experiments were therefore carried out to investigate the thermoregulatory responses of both male (n = 7) and female (n = 7) adult guinea pigs when they were exposed to a simulated open field. Unexpectedly, neither the male nor female guinea pigs developed stress-induced hyperthermia. To the contrary, female but not male guinea pigs significantly decreased their core temperature during an open field experiment. The mechanism of the gender-specific thermoregulatory response of the adult guinea pig to psychological stress is presently unknown.
心理应激的诱导通常伴随着核心体温的短暂升高，通常称为应激诱导性体温过高。虽然当大鼠、小鼠和猪暴露于新异刺激（如模拟旷场、束缚等）时会出现应激诱导性体温过高，但豚鼠是否会出现这种情况尚未得到研究。因此，本实验旨在研究成年雄性（n = 7）和雌性（n = 7）豚鼠暴露于模拟旷场时的体温调节反应。出乎意料的是，雄性和雌性豚鼠均未出现应激诱导性体温过高。相反，在旷场实验中，雌性而非雄性豚鼠的核心体温显著降低。成年豚鼠对心理应激的性别特异性体温调节反应机制目前尚不清楚。
