Kloner R A, Jarow J P
Am J Cardiol. 1999 Feb 15;83(4):576-82, A7. doi: 10.1016/s0002-9149(98)00916-3.
Since the release of sildenafil citrate (Viagra), increasing numbers of patients are seeking treatment for erectile dysfunction (ED). Many of the risk factors for ED are the same as those for cardiac disease. Sildenafil citrate is a highly effective oral agent for ED. It is absolutely contraindicated in patients receiving organic nitrates. The issue of cardiac deaths associated with sildenafil citrate and ways of potentially minimizing these cases are discussed.
自从枸橼酸西地那非(伟哥)上市以来,寻求勃起功能障碍(ED)治疗的患者越来越多。ED的许多风险因素与心脏病的风险因素相同。枸橼酸西地那非是一种治疗ED的高效口服药物。正在接受有机硝酸盐治疗的患者绝对禁用此药。本文讨论了与枸橼酸西地那非相关的心脏死亡问题以及潜在减少这些病例的方法。