Burger A J, Kamalesh M
Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
Am J Cardiol. 1999 Feb 15;83(4):596-8, A8. doi: 10.1016/s0002-9149(98)00921-7.
The circadian rhythm of heart rate variability is present in normal subjects and in patients with angina, with the greatest variation in the normal population and a smaller but significant variation in the anginal group. With beta-adrenergic blockade, significant improvement occurs in all daytime time domain parameters, nocturnal percentage of RR intervals with >50-ms variation, and square root of mean-squared differences of successive RR intervals, daytime total power, and high-frequency band, representing significant improvement in parasympathetic function.
正常受试者和心绞痛患者均存在心率变异性的昼夜节律，正常人群中的变异性最大，心绞痛组的变异性较小但仍显著。使用β-肾上腺素能阻滞剂后，所有日间时域参数、夜间RR间期变异>50毫秒的百分比、连续RR间期均方根差值、日间总功率和高频带均有显著改善，这代表着副交感神经功能有显著改善。
