[The effect of exercise on the androgen receptor binding capacity and the level of testosterone in the skeletal muscle].

Androgen receptor (AR) binding and testosterone (T) level of skeletal muscle of rat at the different conditions were observed in this study. The exhausted exercise could up-regulate the AR binding of levator ani muscle, but decrease the T level in quadriceps. The long term exhausted exercise had no effect on the AR binding of quadriceps. The fitness exercise could up-regulate the AR binding of quadriceps but have no significant effect on the T level in quadriceps. There was no effect on the AR binding but T level was increased after injection of HCG for 4 days in quadriceps. The increase of T level in skeletal muscle after injection of HCG for 4 days was higher than that for 8 days. From these results it is suggested that the effect of exercise on the regulation of hormone on skeletal muscle may be in two directions. Both AR binding capacity and T level must be considered in skeletal muscle anabolism.