[耐力训练和力竭运动对大鼠金属硫蛋白的影响]

[The effect of endurance training and exhaustive exercise on metallothionein in rats].

作者信息

Li Z, Gao Y, Li S, Chen K, Ge S, Pang Y, Tang C

机构信息

Institute of Sports Medicine, Beijing Medical University.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 1997 Feb;13(1):16-7.

PMID:10074301

Abstract

To understand physiological role of metallothionein (MT) during exercise, MT levels in liver, brain, heart, lung, blood vessel, skeletal muscle and serum were observed in rats. The results showed that the levels of MT were decreased by 13-34% in lung, liver, heart and skeletal muscle of rats trained by swimming for 10 weeks and were increased by 21%-75% in skeletal muscle, heart, brain, lung and liver of rats after exhaustive swimming respectively, compared with normal control rats. (P < 0.05 and P < 0.01). But the levels of MT in blood vessel and serum were not changed in two groups of rats by swimming for 10 weeks and acute exhaustive swimming (P > 0.05). It is suggested that the different changes of MT levels under physical training and acute exhaustive exercise may be of importance in protection against oxygen free radicals.

摘要

为了解运动过程中金属硫蛋白（MT）的生理作用，观察了大鼠肝脏、脑、心脏、肺、血管、骨骼肌及血清中MT的水平。结果显示，与正常对照大鼠相比，持续游泳训练10周的大鼠肺、肝脏、心脏和骨骼肌中MT水平降低了13% - 34%，力竭游泳后的大鼠骨骼肌、心脏、脑、肺和肝脏中MT水平分别升高了21% - 75%。（P < 0.05和P < 0.01）。但持续游泳10周及急性力竭游泳两组大鼠血管和血清中MT水平均无变化（P > 0.05）。提示体育锻炼和急性力竭运动时MT水平的不同变化可能对抵御氧自由基具有重要意义。