原子力显微镜：研究单分子的有力方法。

Atomic force microscopy: a forceful way with single molecules.

作者信息

Engel A, Gaub H E, Müller D J

机构信息

M.E. Müller-Institute for Microscopy Biozentrum University of Basel Klingelbergstrasse 70 CH-4056 Basel Switzerland.

出版信息

Curr Biol. 1999 Feb 25;9(4):R133-6. doi: 10.1016/s0960-9822(99)80081-5.

DOI:10.1016/s0960-9822(99)80081-5

PMID:10074420

Abstract

The atomic force microscope (AFM) now routinely provides images that reveal subnanometer surface structures of biomolecules. The sensitivity and precision of AFM provide new opportunities for studying the mechanical properties of biomolecules and their interactions in their native environment.

摘要

原子力显微镜（AFM）现在经常能提供揭示生物分子亚纳米表面结构的图像。AFM的灵敏度和精度为研究生物分子的力学性质及其在天然环境中的相互作用提供了新的机会。