Rouse D J, Owen J, Hauth J C
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, USA.
Obstet Gynecol. 1999 Mar;93(3):323-8. doi: 10.1016/s0029-7844(98)00448-7.
To assess a labor-management protocol that mandated at least 4 hours of oxytocin augmentation before cesarean delivery for active-phase labor arrest.
We prospectively evaluated term gravidas in spontaneous labor with active-phase labor arrest (cervix at least 4 cm dilated and 1 cm or less of cervical progress in 2 hours). Exclusion criteria included nonvertex presentation, previous cesarean, multiple gestation, and a nonreassuring fetal heart rate tracing or chorioamnionitis at the time of labor arrest. After the diagnosis of active-phase arrest, oxytocin was initiated with an intent to achieve a sustained uterine contraction pattern of greater than 200 Montevideo units. Cesarean delivery was not performed for labor arrest until at least 4 hours of a sustained uterine contraction pattern of greater than 200 Montevideo units, or a minimum of 6 hours of oxytocin augmentation if this contraction pattern could not be achieved.
Five hundred forty-two women were managed by the protocol, and 92% delivered vaginally. The subsequent vaginal delivery rate for parous women who had not progressed (1 cm of cervical dilation or less) despite 2 hours of oxytocin augmentation was 91%, and it was 74% for nulliparas. With no labor progress after 4 hours of oxytocin augmentation, the subsequent vaginal delivery rates were 88% for parous women and 56% for nulliparas. There were no severe maternal complications. One neonate had persistent fetal circulation and one had a positive blood culture, but both did well.
Extending the minimum period of oxytocin augmentation for active-phase labor arrest from 2 to at least 4 hours was effective and safe.
评估一项劳动管理方案,该方案规定在剖宫产分娩前,对于活跃期产程停滞至少进行4小时的缩宫素增强治疗。
我们前瞻性地评估了足月自然分娩且处于活跃期产程停滞(宫颈扩张至少4厘米,2小时内宫颈进展1厘米或更少)的孕妇。排除标准包括非头位、既往剖宫产史、多胎妊娠以及产程停滞时胎儿心率监护异常或绒毛膜羊膜炎。在诊断为活跃期停滞后,开始使用缩宫素,目的是实现持续的子宫收缩模式,超过200蒙氏单位。在子宫收缩模式持续超过200蒙氏单位至少4小时之前,或在无法达到这种收缩模式时至少进行6小时的缩宫素增强治疗之前,不进行剖宫产分娩以处理产程停滞。
542名妇女按照该方案进行管理,92%经阴道分娩。尽管使用缩宫素增强治疗2小时后未进展(宫颈扩张1厘米或更小)的经产妇随后的阴道分娩率为91%,初产妇为74%。在缩宫素增强治疗4小时后仍无产程进展时,经产妇随后的阴道分娩率为88%,初产妇为56%。没有严重的母体并发症。一名新生儿有持续性胎儿循环,一名血培养阳性,但两人情况均良好。
将活跃期产程停滞的缩宫素增强最短时间从2小时延长至至少4小时是有效且安全的。