Tervaniemi M, Kujala A, Alho K, Virtanen J, Ilmoniemi R J, Näätänen R
Department of Psychology, University of Helsinki, Helsinki, Finland.
Neuroimage. 1999 Mar;9(3):330-6. doi: 10.1006/nimg.1999.0405.
Functional specialization of the human auditory cortex in processing phonetic vs musical sounds was investigated. While subjects watched a silent self-selected movie, they were presented with sequences consisting of frequent and infrequent phonemes (/e/ and /o/, respectively) or chords (A major and A minor, respectively). The subjects' brain responses to these sounds were recorded with a 122-channel whole-head magnetometer. The data indicated that within the right hemisphere, the magnetoencephalographic (MEG) counterpart MMNm of the mismatch negativity (MMN) elicited by an infrequent chord change was stronger than the MMNm elicited by a phoneme change. Within the left hemisphere, the MMNm strength for a chord vs phoneme change did not significantly differ. Furthermore, the MMNm sources for the phoneme and chord changes were posterior to the P1m sources generated at or near the primary auditory areas. In addition, the MMNm source for a phoneme change was superior to that for the chord change in both hemispheres. The data thus provide evidence for spatially distinct cortical areas in both hemispheres specialized in representing phonetic and musical sounds.
研究了人类听觉皮层在处理语音与音乐声音方面的功能特化。当受试者观看一部无声的自选电影时，他们会听到由频繁和不频繁出现的音素（分别为/e/和/o/）或和弦（分别为A大调和弦和A小调和弦）组成的序列。用122通道全头磁强计记录受试者对这些声音的大脑反应。数据表明，在右半球，由不频繁的和弦变化引发的失匹配负波（MMN）的脑磁图（MEG）对应物MMNm比由音素变化引发的MMNm更强。在左半球，和弦与音素变化的MMNm强度没有显著差异。此外，音素和和弦变化的MMNm源位于初级听觉区域或其附近产生的P1m源的后方。另外，在两个半球中，音素变化的MMNm源都高于和弦变化的MMNm源。这些数据因此为两个半球中专门用于表征语音和音乐声音的空间上不同的皮层区域提供了证据。
