语音分析中的半球侧化。在日本受试者中重现了左半球优势。

Hemispheric lateralization in an analysis of speech sounds. Left hemisphere dominance replicated in Japanese subjects.

作者信息

Koyama S, Gunji A, Yabe H, Oiwa S, Akahane-Yamada R, Kakigi R, Näätänen R

机构信息

Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444-8585, Aichi, Japan.

出版信息

Brain Res Cogn Brain Res. 2000 Sep;10(1-2):119-24. doi: 10.1016/s0926-6410(00)00034-3.

DOI:10.1016/s0926-6410(00)00034-3

PMID:10978699

Abstract

Evoked magnetic responses to speech sounds [R. Näätänen, A. Lehtokoski, M. Lennes, M. Cheour, M. Huotilainen, A. Iivonen, M. Vainio, P. Alku, R.J. Ilmoniemi, A. Luuk, J. Allik, J. Sinkkonen and K. Alho, Language-specific phoneme representations revealed by electric and magnetic brain responses. Nature, 385 (1997) 432-434.] were recorded from 13 Japanese subjects (right-handed). Infrequently presented vowels ([o]) among repetitive vowels ([e]) elicited the magnetic counterpart of mismatch negativity, MMNm (Bilateral, nine subjects; Left hemisphere alone, three subjects; Right hemisphere alone, one subject). The estimated source of the MMNm was stronger in the left than in the right auditory cortex. The sources were located posteriorly in the left than in the right auditory cortex. These findings are consistent with the results obtained in Finnish [R. Näätänen, A. Lehtokoski, M. Lennes, M. Cheour, M. Huotilainen, A. Iivonen, M.Vainio, P.Alku, R.J. Ilmoniemi, A. Luuk, J. Allik, J. Sinkkonen and K. Alho, Language-specific phoneme representations revealed by electric and magnetic brain responses. Nature, 385 (1997) 432-434.][T. Rinne, K. Alho, P. Alku, M. Holi, J. Sinkkonen, J. Virtanen, O. Bertrand and R. Näätänen, Analysis of speech sounds is left-hemisphere predominant at 100-150 ms after sound onset. Neuroreport, 10 (1999) 1113-1117.] and English [K. Alho, J.F. Connolly, M. Cheour, A. Lehtokoski, M. Huotilainen, J. Virtanen, R. Aulanko and R.J. Ilmoniemi, Hemispheric lateralization in preattentive processing of speech sounds. Neurosci. Lett., 258 (1998) 9-12.] subjects. Instead of the P1m observed in Finnish [M. Tervaniemi, A. Kujala, K. Alho, J. Virtanen, R.J. Ilmoniemi and R. Näätänen, Functional specialization of the human auditory cortex in processing phonetic and musical sounds: A magnetoencephalographic (MEG) study. Neuroimage, 9 (1999) 330-336.] and English [K. Alho, J. F. Connolly, M. Cheour, A. Lehtokoski, M. Huotilainen, J. Virtanen, R. Aulanko and R.J. Ilmoniemi, Hemispheric lateralization in preattentive processing of speech sounds. Neurosci. Lett., 258 (1998) 9-12.] subjects, prior to the MMNm, M60, was elicited by both rare and frequent sounds. Both MMNm and M60 sources were posteriorly located in the left than the right hemisphere.

摘要

对语音的诱发磁反应[R. 纳塔南、A. 莱托科斯基、M. 伦内斯、M. 乔尔、M. 胡蒂莱宁、A. 伊沃宁、M. 瓦尼奥、P. 阿尔库、R.J. 伊尔莫尼埃米、A. 卢克、J. 阿利克、J. 辛科宁和K. 阿尔霍，脑电和脑磁反应揭示的语言特异性音素表征。《自然》，385 (1997) 432 - 434。]记录自13名日本受试者（右利手）。在重复的元音（[e]）中偶尔出现的元音（[o]）引发了失配负波的磁对应物，即MMNm（双侧，9名受试者；仅左侧半球，3名受试者；仅右侧半球，1名受试者）。MMNm的估计源在左侧听觉皮层比右侧更强。这些源在左侧听觉皮层比右侧更靠后。这些发现与在芬兰人[R. 纳塔南、A. 莱托科斯基、M. 伦内斯、M. 乔尔、M. 胡蒂莱宁、A. 伊沃宁、M. 瓦尼奥、P. 阿尔库、R.J. 伊尔莫尼埃米、A. 卢克、J. 阿利克、J. 辛科宁和K. 阿尔霍，脑电和脑磁反应揭示的语言特异性音素表征。《自然》，385 (1997) 432 - 434。][T. 林内、K. 阿尔霍、P. 阿尔库、M. 霍利、J. 辛科宁、J. 维尔塔宁、O. 贝特朗和R. 纳塔南，声音起始后100 - 150毫秒时语音分析以左半球为主。《神经报告》，10 (1999) 1113 - 1117。]和英国人[K. 阿尔霍、J.F. 康诺利、M. 乔尔、A. 莱托科斯基、M. 胡蒂莱宁、J. 维尔塔宁、R. 奥兰卡和R.J. 伊尔莫尼埃米，语音前注意加工中的半球侧化。《神经科学快报》，258 (1998) 9 - 12。]中获得的结果一致。与在芬兰人[M. 特尔瓦涅米、A. 库亚拉、K. 阿尔霍、J. 维尔塔宁、R.J. 伊尔莫尼埃米和R. 纳塔南，人类听觉皮层在处理语音和音乐声音方面的功能特化：一项脑磁图（MEG）研究。《神经影像学》，9 (1999) 330 - 336。]和英国人[K. 阿尔霍、J.F. 康诺利、M. 乔尔、A. 莱托科斯基、M. 胡蒂莱宁、J. 维尔塔宁、R. 奥兰卡和R.J. 伊尔莫尼埃米，语音前注意加工中的半球侧化。《神经科学快报》，258 (1998) 9 - 12。]中观察到的P1m不同，在MMNm之前，罕见和频繁出现的声音都会引发M60。MMNm和M60的源在左侧半球比右侧半球更靠后。