• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[丙烷 - 二醇 -(1,3)脂肪酸酯作为死后甘油三酯分解代谢的代谢产物(作者译)]

[Propane-diol-(1.3) fatty acid esters as metabolites of postmortal triglyceride catabolism (author's transl)].

作者信息

Döring G, Lackner H, Mieskes G, Vogel R

出版信息

Z Rechtsmed. 1976;78(4):285-96. doi: 10.1007/BF01869231.

DOI:10.1007/BF01869231
PMID:1007631
Abstract

The investigation of 72 samples of human subcutaneous fat tissue stored in closed small bottles at room temperature showed that every third sample decomposed with the formation of unknown metabolites. The presence of these compounds could already be recognized in the crude lipid extracts by characteristic 1H-NMR signals, increasing in intensity with time of storage. After isolation, the unknown metabolites could be identified as di- or mono fatty acid esters of propane-diol-(1.3). Thus, the known scheme of postmortal breakdown of triglycerides is to be supplemented by a further remarkable pathway.

摘要

对72份储存在密闭小瓶中、室温下的人体皮下脂肪组织样本进行的调查显示,每三个样本中就有一个会分解并形成未知代谢产物。这些化合物的存在在粗脂质提取物中就可以通过特征性的1H-NMR信号识别出来,其强度会随着储存时间的增加而增强。分离后,这些未知代谢产物可被鉴定为丙二醇-(1,3)的二脂肪酸酯或单脂肪酸酯。因此,已知的甘油三酯死后分解方案需要通过另一条显著的途径来补充。

相似文献

1
[Propane-diol-(1.3) fatty acid esters as metabolites of postmortal triglyceride catabolism (author's transl)].[丙烷 - 二醇 -(1,3)脂肪酸酯作为死后甘油三酯分解代谢的代谢产物(作者译)]
Z Rechtsmed. 1976;78(4):285-96. doi: 10.1007/BF01869231.
2
On the generation and outcome of 3-(N-phenylamino)propane-1,2-diol derivatives in deodorized model oils related to toxic oil syndrome.与有毒油综合征相关的脱臭模型油中3-(N-苯基氨基)丙烷-1,2-二醇衍生物的生成及结果
Chem Res Toxicol. 2005 Apr;18(4):665-74. doi: 10.1021/tx0497595.
3
[Diol lipids. Neutral diol lipids from regenerating rat liver].[二醇脂质。来自再生大鼠肝脏的中性二醇脂质]
Biokhimiia. 1971 May-Jun;36(3):623-9.
4
Metabolism of (R)- and (S)-3-(phenylamino)propane-1,2-diol in C57BL/6- and A/J-strain mice. Identification of new metabolites with potential toxicological significance to the toxic oil syndrome.(R)-和(S)-3-(苯氨基)丙烷-1,2-二醇在C57BL/6和A/J品系小鼠中的代谢。对有毒油综合征具有潜在毒理学意义的新代谢物的鉴定。
Chem Res Toxicol. 2001 Aug;14(8):1097-106. doi: 10.1021/tx010001k.
5
[Experimental poisoning with gaseous hydrocarbons: changes in concentrations of propane and butane in the lung and adipose tissue in relation to the time of death].[气态烃类实验性中毒:肺和脂肪组织中丙烷和丁烷浓度随死亡时间的变化]
Boll Soc Ital Biol Sper. 1979 Jan 15;55(1):38-41.
6
Studies on toxic oil syndrome: stereoselective hydrolysis of 3-(phenylamino)propane-1,2-diol esters by human pancreatic lipase.毒油综合征的研究:人胰脂肪酶对3-(苯氨基)丙烷-1,2-二醇酯的立体选择性水解
Chem Res Toxicol. 2004 Jul;17(7):889-95. doi: 10.1021/tx049952z.
7
Does the composition of propane-1,2-diol alter over time?1,2 - 丙二醇的成分会随时间变化吗?
J Assist Reprod Genet. 1996 Jan;13(1):53-5. doi: 10.1007/BF02068870.
8
Adipose tissue fatty acid storage factors: effects of depot, sex and fat cell size.脂肪组织脂肪酸储存因子:储存部位、性别及脂肪细胞大小的影响
Int J Obes (Lond). 2015 Jun;39(6):884-7. doi: 10.1038/ijo.2015.10. Epub 2015 Feb 6.
9
Proceedings: The action of alpha-chlorohydrin (3-chloro-propane 1,2-diol) on the metabolism of glycerol in male rats.论文:α-氯醇(3-氯-1,2-丙二醇)对雄性大鼠甘油代谢的作用
J Reprod Fertil. 1973 Dec;35(3):589-90. doi: 10.1530/jrf.0.0350589.
10
[In vivo and in vitro triglyceride breakdown in man (author's transl)].人体体内和体外甘油三酯的分解(作者译)
Cas Lek Cesk. 1974 Feb 8;113(6):165-8.

引用本文的文献

1
[Postmortem decomposition of neutral lipids. Use of modern methods of analysis (HPLC, capillary GC, GC-MS and NMR) in adipocere formation].[中性脂质的死后分解。现代分析方法(高效液相色谱法、毛细管气相色谱法、气相色谱-质谱联用仪和核磁共振)在尸蜡形成中的应用]
Z Rechtsmed. 1985;94(4):273-87. doi: 10.1007/BF00205095.

本文引用的文献

1
[Cleavage of higher triglyceride fatty acids during autolysis of adipose tissue].[脂肪组织自溶过程中较高甘油三酯脂肪酸的裂解]
Hoppe Seylers Z Physiol Chem. 1968 Nov;349(11):1493-6.