Alamowitch B, Mausset V, Ruiz A, Tissier F, Fourmestraux J, Bouillot J L, Bethoux J P
Service de Chirurgie digestive, Hôtel-Dieu de Paris.
Presse Med. 1999 Feb 6;28(5):225-8.
Non-secreting pheochromocytoma is an endocrine tumor located in the adrenal medulla in 85% of the cases. Extra-adrenal localizations account for the other 15%. A broad ligament localization related to an accessory adrenal gland is exceptional.
A tumoral formation was observed during computed tomographic exploration of appendicular peritonitis in a 25-year-old patient. The tumor had developed from an ectopic adrenal gland included in the large ligament of the uterus. Pathology reported non-secreting pheochromocytoma confirmed by immunolabeling.
The broad ligament localization is exceptional for pheochromocytomas and may mislead diagnosis. Resection is the only treatment. Recurrence and metastases have been reported to develop in some cases many years later, particularly after incomplete resection. Pathogenically, this tumor is remnant embryonic chromaffin tissue issuing from the parasympathetic nodes and developing in an ectopic adrenal gland.
非分泌性嗜铬细胞瘤是一种内分泌肿瘤，85%的病例位于肾上腺髓质，其余15%为肾上腺外定位。与副肾上腺相关的阔韧带定位极为罕见。
在对一名25岁患者的阑尾腹膜炎进行计算机断层扫描检查时发现了一个肿瘤形成。该肿瘤由子宫阔韧带内的异位肾上腺发展而来。病理报告为非分泌性嗜铬细胞瘤，经免疫标记证实。
嗜铬细胞瘤的阔韧带定位极为罕见，可能会误导诊断。手术切除是唯一的治疗方法。据报道，在某些情况下，多年后尤其是不完全切除后会发生复发和转移。从发病机制上讲，这种肿瘤是源于副交感神经节的残留胚胎嗜铬组织，并在异位肾上腺中发展。
