Beardsley M, Deren S, Tortu S, Goldstein M F, Ziek K, Hamid R
National Development and Research Institutes, Inc., New York, New York 10048, USA.
J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Mar 1;20(3):283-9. doi: 10.1097/00042560-199903010-00011.
This study assessed the relation between year of recruitment into an AIDS prevention project and likelihood of engaging (yes/no) in injection risk behaviors.
In total, 834 injection drug users were recruited over a 44-month period (January 1992-August 1995) in New York City. Logistic regression was used to examine trends in three behaviors, across four successive annual cohorts: using needles/syringes that were previously used by another person, using injection supplies (e.g., cookers, cotton, rinse water) that had been previously used, and giving or lending of used needles/syringes to another person.
Significant (p < .0001) decreasing trends occurred in two behaviors: giving or lending of used needles/syringes to another person and use of injection supplies that had been used by another person. Sample characteristics were generally consistent over time and did not obviate significant injection risk trends.
Decreasing trends in injection risk behaviors could not be explained by changing sample characteristics. Even though some injectors report engaging in risky injection practices, the confluence of numerous AIDS prevention efforts in the 1990s has contributed to an overall reduction in the likelihood of such behaviors.
本研究评估了参与艾滋病预防项目的年份与进行注射风险行为（是/否）的可能性之间的关系。
1992年1月至1995年8月的44个月期间，在纽约市共招募了834名注射吸毒者。采用逻辑回归分析四个连续年度队列中三种行为的趋势：使用他人用过的针头/注射器、使用他人用过的注射用品（如煮器、棉花、冲洗水）以及将用过的针头/注射器给予或借给他人。
两种行为出现了显著（p <.0001）的下降趋势：将用过的针头/注射器给予或借给他人以及使用他人用过的注射用品。样本特征随时间总体保持一致，并未消除显著的注射风险趋势。
注射风险行为的下降趋势无法用样本特征的变化来解释。尽管一些注射者报告有危险的注射行为，但20世纪90年代众多艾滋病预防工作的共同作用导致此类行为的可能性总体下降。
