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北斯塔福德郡自杀研究:一项关于一个健康区自杀情况的病例对照研究。

The North Staffordshire Suicide Study: a case-control study of suicide in one health district.

作者信息

Boardman A P, Grimbaldeston A H, Handley C, Jones P W, Willmott S

机构信息

Division of Psychiatry and Psychology, Guy's Hospital, London.

出版信息

Psychol Med. 1999 Jan;29(1):27-33. doi: 10.1017/s0033291798007430.

Abstract

BACKGROUND

The aim of the study was to identify sociodemographic and clinical risk factors for death from suicide and undetermined injury in residents of one health district.

METHOD

Data were collected on all cases of suicide (ICD-9 E950-959) and undetermined injury (ICD-9 E980-989) for residents in North Staffordshire Health District between 1991 and 1995. Controls identified from the Coroner's inquest register, who died from other causes, were matched for age and sex.

RESULTS

Two hundred and twelve pairs of cases and matched controls were identified. Multivariate analysis (conditional logistic regression) showed that the risk of death due to suicide and undetermined death was associated with: recent separation, relationship difficulties, experience of financial difficulties, history of past criminal charges or contact with the police, a past history of deliberate self-harm, being on psychotropic medication at the time of death and a diagnosis of bipolar affective disorder. For sociodemographic variables, a univariate analysis found associations between the cases and being separated, living alone, having a past history of criminal charges and unemployment. Cases were more likely to have a psychiatric disorder, past history of deliberate self-harm and a past history of psychiatric contact for themselves or a family member. Controls were more likely to have a current medical disorder. Cases were more likely than controls to be on any form of medication at the time of death and to have received a prescription for psychotropic or non-psychotropic medication in the week and month before death. Cases were more likely than controls to have had contact with medical services in the week and month before death, with the general practitioner in the week before death and with psychiatric services at any time in the year before death. Strong associations were found between suicide and undetermined injury and life events such as recent separation and bereavement, and financial and relationship difficulties.

CONCLUSIONS

The study provides an analytical investigation utilizing a dead control group, data gathered from several sources and adequate numbers of cases. It confirms many of the risk factors identified in other studies and highlights the high proportion of suicides who have been in recent contact with the criminal justice system or have been prescribed medication shortly before death.

摘要

背景

本研究旨在确定某一健康区居民自杀及不明原因损伤死亡的社会人口学和临床风险因素。

方法

收集了1991年至1995年北斯塔福德郡健康区居民所有自杀(国际疾病分类第九版E950 - 959)和不明原因损伤(国际疾病分类第九版E980 - 989)病例的数据。从死因裁判官调查登记册中确定的死于其他原因的对照者,按年龄和性别进行匹配。

结果

共确定了212对病例与匹配对照。多变量分析(条件逻辑回归)显示,自杀和不明原因死亡的风险与以下因素相关:近期分居、关系问题、经济困难经历、过去的刑事指控或与警方接触史、既往故意自伤史、死亡时正在服用精神药物以及双相情感障碍诊断。对于社会人口学变量,单变量分析发现病例与分居、独居、有过去刑事指控史和失业之间存在关联。病例更有可能患有精神疾病、有既往故意自伤史以及本人或家庭成员有既往精神科就诊史。对照者更有可能患有当前的躯体疾病。病例在死亡时比对照者更有可能正在服用任何形式的药物,并且在死亡前一周和一个月内接受过精神药物或非精神药物处方。病例在死亡前一周和一个月内比对照者更有可能与医疗服务机构有接触,在死亡前一周与全科医生有接触,在死亡前一年的任何时间与精神科服务机构有接触。自杀和不明原因损伤与近期分居和丧亲等生活事件以及经济和关系问题之间存在强烈关联。

结论

本研究利用死亡对照组、从多个来源收集的数据以及足够数量的病例进行了分析调查。它证实了其他研究中确定的许多风险因素,并突出了近期与刑事司法系统有接触或在死亡前不久被开了药的自杀者的高比例。

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