[Morphological changes in the stomach and duodenum in ulcer disease with Helicobacter infection].

In 119 gastroduodenal ulcer disease (UD) patients the presence of Helicobacter pylori (HP) was determined and the morphological changes of gastric mucosa were studied up. The rapid test with urease, cytological investigation of the smear prints and histological examination of the operational material biopsies were done for the HP elimination detection. In gastric UD with nonsignificant HP dissemination the mucosal morphological changes are limited mainly by the cell infiltration of various degree. While the duodenal UD observation, as a rule, there were revealed the HP dissemination of the III-IV degree and significant morphological changes, extended in deep layers of gastric wall, stroma, significant dystrophic and necrobiotic processes in superficial layer.