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[溃疡性消化不良患者中的幽门螺杆菌]

[Helicobacter pylori in patients with ulcerative dyspepsia].

作者信息

Copercido J B, Cabral D H, Martiarena M H

机构信息

Centro de Diagnóstico de Enfermedades Digestivas, Necochea, Provincia de Buenos Aires.

出版信息

Acta Gastroenterol Latinoam. 1992;22(4):221-6.

PMID:1340676
Abstract

A group of consecutive patients with ulcer dyspepsia were studied by endoscopy, antral and duodenal biopsy; by histologic determination of Helicobacter pylori (HP) and by silver staining (Warthin Starry technique). 68.31% were found to be infected. In those patients who showed chronic antritis (69.30% of the patients), HP was present in 92.85% of cases. In gastric and duodenal ulcer patients, similar rates were shown (76.47% and 76.92% respectively. In cases with normal histology findings HP was present in only 12.90% of cases. In the duodenum HP was scarce (7.92%) and there was always concomitant metaplasias. HP is strongly linked with mucosal lesions in our patients with ulcer dyspepsia. We wonder its responsibility in producing these lesions and about the need of performing specific treatment against HP in this patients.

摘要

对一组连续性溃疡消化不良患者进行了内镜检查、胃窦和十二指肠活检;通过组织学方法测定幽门螺杆菌(HP)并采用银染色法(沃辛-斯塔瑞技术)。发现68.31%的患者受到感染。在那些表现为慢性胃窦炎的患者中(占患者总数的69.30%),92.85%的病例中存在HP。在胃溃疡和十二指肠溃疡患者中,显示出相似的感染率(分别为76.47%和76.92%)。在组织学检查结果正常的病例中,仅12.90%的病例存在HP。在十二指肠中,HP较少见(7.92%),且总是伴有化生。在我们的溃疡消化不良患者中,HP与黏膜病变密切相关。我们怀疑其在产生这些病变中的作用,以及在这些患者中针对HP进行特异性治疗的必要性。

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