Ohori N, Kusunoki S, Ohta M
Department of Neurology, Hiroshima Red Cross Hospital.
Rinsho Shinkeigaku. 1998 Sep;38(9):843-5.
This is a case report of atypical Guillain-Barré syndrome (GBS). A 42-year-old woman displayed pharyngeal paralysis after a mild upper respiratory infection, subsequently having developed ophthalmoplegia, facial diplegia and accessory nerve palsy within about ten days. She had neither weakness nor abnormal tendon reflexes in the extremities. During the acute phase of the disease we found significant elevation of anti-GQ1b and anti-GT1a IgG antibodies in the serum, and immunoadsorption therapy had a remarkable effect on the symptoms. Although our case was extremely atypical of GBS in terms of exclusively showing multiple cranial nerve palsy and lacking areflexia, the elevation of anti-glycolipid antibodies during the acute phase suggests that this case shares pathogenesis with GBS.
这是一例非典型吉兰-巴雷综合征（GBS）的病例报告。一名42岁女性在轻度上呼吸道感染后出现咽麻痹，随后在约十天内发展为眼肌麻痹、双侧面瘫和副神经麻痹。她的四肢既没有无力症状，腱反射也未异常。在疾病急性期，我们发现血清中抗GQ1b和抗GT1a IgG抗体显著升高，免疫吸附治疗对症状有显著效果。尽管我们的病例在仅表现为多发性颅神经麻痹且无反射消失方面极不典型，但急性期抗糖脂抗体升高表明该病例与GBS有共同的发病机制。
