[A case of atypical Guillain-Barré syndrome exclusively showing multiple cranial nerve palsy with an elevation of anti-GQ1b and anti-GT1a IgG antibodies].

This is a case report of atypical Guillain-Barré syndrome (GBS). A 42-year-old woman displayed pharyngeal paralysis after a mild upper respiratory infection, subsequently having developed ophthalmoplegia, facial diplegia and accessory nerve palsy within about ten days. She had neither weakness nor abnormal tendon reflexes in the extremities. During the acute phase of the disease we found significant elevation of anti-GQ1b and anti-GT1a IgG antibodies in the serum, and immunoadsorption therapy had a remarkable effect on the symptoms. Although our case was extremely atypical of GBS in terms of exclusively showing multiple cranial nerve palsy and lacking areflexia, the elevation of anti-glycolipid antibodies during the acute phase suggests that this case shares pathogenesis with GBS.