Bridgewater B, Steyn R S, Ray S, Hooper T
Department of Cardiothoracic Surgery, Wythenshawe Hospital, Manchester, UK.
Heart. 1998 Jun;79(6):605-7. doi: 10.1136/hrt.79.6.605.
To compare aortic valve replacement (AVR) using a minimally invasive approach through a transverse sternotomy with the established approach of median sternotomy.
Retrospective, case-control study.
Fourteen high risk patients (median age 78, Parsonnet score of 18%) who underwent AVR performed through a minimally invasive transverse sternotomy were compared with a historical group of patients matched for age, sex, and Parsonnet score who underwent AVR performed through a median sternotomy by the same surgeon.
Cross clamp time, total bypass time, intensive care stay, postoperative in-hospital stay, morbidity, and mortality.
There were two deaths in the minimally invasive group and none in the control group (NS). The cross clamp and total bypass times were longer in the minimally invasive group (67 and 92 minutes v 46 and 66 minutes, p < 0.001). There was a higher incidence of re-exploration for bleeding (14% v 0%) and paravalvar leaks (21% v 0%) in the minimally invasive group but these differences were not significant. The minimally invasive group had a longer postoperative in-hospital stay (p = 0.025). The incidence of mortality or major morbidity was 43% (six of 14) in the minimally invasive group and 7% (one of 14) in the matched pairs (p = 0.013).
AVR can be performed through a transverse sternotomy but the operation takes longer and there is an unacceptably high incidence of morbidity and mortality.
比较经横向胸骨切开的微创方法行主动脉瓣置换术(AVR)与传统的正中胸骨切开术。
回顾性病例对照研究。
14例高危患者(中位年龄78岁,Parsonnet评分为18%)接受了经微创横向胸骨切开的AVR,与一组年龄、性别和Parsonnet评分相匹配的历史患者组进行比较,后者由同一位外科医生经正中胸骨切开进行AVR。
主动脉阻断时间、体外循环总时间、重症监护病房停留时间、术后住院时间、发病率和死亡率。
微创组有2例死亡,对照组无死亡(无统计学差异)。微创组的主动脉阻断和体外循环总时间更长(分别为67分钟和92分钟,对比46分钟和66分钟,p<0.001)。微创组再次开胸止血(14%对比0%)和瓣周漏(21%对比0%)的发生率更高,但这些差异无统计学意义。微创组术后住院时间更长(p = 0.025)。微创组的死亡率或主要并发症发生率为43%(14例中的6例),配对组为&7%(14例中的1例)(p = 0.013)。
AVR可通过横向胸骨切开进行,但手术时间更长,发病率和死亡率高得令人难以接受。