Hammoudi-Bendib N, Bourezak S E, Issad M S
Service de cardiologie, CHU Mustapha, Alger Centre, Algérie.
Arch Mal Coeur Vaiss. 1999 Feb;92(2):269-71.
The authors report a very rare case of massive haemolytic anaemia complicated by renal failure in a patient with a double aortic and mitral bioprosthesis. The haemolysis was attributed to degeneration of the aortic bioprosthesis causing turbulent flow, aggravated by associated infectious endocarditis. The essential condition for haemolysis is a change in blood flow through the valve by degeneration or other associated pathology. The haemolytic anaemia completely regressed after aortic valve replacement as did the renal failure.