Wiltse L L, Radecki S E, Biel H M, DiMartino P P, Oas R A, Farjalla G, Ravessoud F A, Wohletz C
Department of Orthopedics, University of California Irvine, USA.
J Spinal Disord. 1999 Feb;12(1):27-33.
The purpose of this study was to determine whether the addition of pedicle screws and rods to a fusion of two or more vertebrae of the lowest three motion segments of the lumbar spine increases the incidence or severity of transition zone change (TZC) above or below the fused area. A study group of 52 patients who had a fusion with fixation and a control group of 31 who had a nearly identical operation but without fixation were obtained. Radiographs and computed tomography scans of the area of study were taken preoperatively and were repeated approximately 7 years after the operation. Results showed that the addition of pedicle screw fixation does not increase the incidence or severity of TZC in the first 7 years after surgery.
本研究的目的是确定在腰椎最低三个活动节段的两个或更多椎体融合术中添加椎弓根螺钉和棒是否会增加融合区域上方或下方过渡区改变（TZC）的发生率或严重程度。选取了52例接受融合内固定手术的患者作为研究组，以及31例接受几乎相同手术但未进行内固定的患者作为对照组。术前对研究区域进行了X线片和计算机断层扫描，并在术后约7年重复进行。结果显示，在术后的前7年，添加椎弓根螺钉固定并不会增加TZC的发生率或严重程度。
