Hildebrandt H, Brand A, Sachsenheimer W
Health Research Unit, Ossietzky University Oldenburg, Germany.
J Clin Exp Neuropsychol. 1998 Oct;20(5):673-83. doi: 10.1076/jcen.20.5.673.1119.
We compared memory disorders of three patient groups suffering from brain lesions with a word list corresponding to the California Verbal Learning Test (CVLTgcor). Dependent measures were learning rate and efficiency, retention, and strategic control of the learning process. Compared to a control group of patients with right hemispheric lesions, a left Arteria cerebri posterior (LACP) group showed general memory deficits, an inflated recency effect, and increased serial clustering. A left prefrontal cortex (LPFC) group documented slowed learning and increased recall after semantic cues. Discriminant analysis correctly classified 86.11% of the patients. It is argued that (a) the CVLT helps to cover differences in memory disorders recently discussed in cognitive neuropsychology; (b) differences between PFC and ACP patients become evident only if strategic aspects of learning and increased recall after semantic cueing are taken into account. The results are discussed within the framework of recent cognitive neuropsychological findings and with a distinction between fronto-subcortical and cortical memory disorders.
我们使用与加利福尼亚言语学习测验（CVLTgcor）对应的单词列表，比较了三组患有脑部病变患者的记忆障碍情况。相关测量指标包括学习速度和效率、记忆保持以及学习过程的策略控制。与右侧半球病变患者的对照组相比，左脑后动脉（LACP）组表现出一般性记忆缺陷、过度的近因效应以及序列聚类增加。左前额叶皮层（LPFC）组记录到学习速度减慢以及语义线索提示后回忆增加。判别分析正确分类了86.11%的患者。研究认为：（a）CVLT有助于涵盖认知神经心理学近期讨论的记忆障碍差异；（b）只有考虑到学习的策略方面以及语义线索提示后回忆增加的情况，前额叶皮层（PFC）和脑后动脉（ACP）患者之间的差异才会显现。本文在近期认知神经心理学研究结果的框架内，并区分了额叶-皮层下记忆障碍和皮层记忆障碍来讨论这些结果。
