Pathways of Egr-1-mediated gene transcription in vascular biology.
作者信息
Silverman E S, Collins T
机构信息
Pulmonary and Critical Care Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
出版信息
Am J Pathol. 1999 Mar;154(3):665-70. doi: 10.1016/S0002-9440(10)65312-6.
Abstract
摘要
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Left main coronary artery stenosis after percutaneous transluminal coronary angioplasty: importance of remaining "minimally invasive".经皮腔内冠状动脉成形术后左主干冠状动脉狭窄：保持“微创”的重要性。
Catheter Cardiovasc Interv. 1999 Feb;46(2):254-5. doi: 10.1002/(SICI)1522-726X(199902)46:2<254::AID-CCD29>3.0.CO;2-N.
2
Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2.损伤诱导的早期生长反应因子-1是由成纤维细胞生长因子-2的释放和旁分泌激活所触发的。
Am J Pathol. 1999 Mar;154(3):937-44. doi: 10.1016/S0002-9440(10)65341-2.
3
The human copper-zinc superoxide dismutase gene (SOD1) proximal promoter is regulated by Sp1, Egr-1, and WT1 via non-canonical binding sites.人类铜锌超氧化物歧化酶基因（SOD1）近端启动子通过非典型结合位点受Sp1、Egr-1和WT1调控。
J Biol Chem. 1999 Jan 1;274(1):503-9. doi: 10.1074/jbc.274.1.503.
4
Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.雌激素通过调节早期生长反应蛋白-1（Egr-1）的磷酸化及其与特异性蛋白-1（Sp-1）的相互作用，阻断巨噬细胞集落刺激因子（M-CSF）基因表达和破骨细胞形成。
J Clin Invest. 1998 Nov 15;102(10):1850-9. doi: 10.1172/JCI4561.
5
cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1).环磷酸腺苷反应元件结合蛋白结合蛋白（CBP）和p300是早期生长反应因子-1（Egr-1）的转录共激活因子。
Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):183-9. doi: 10.1042/bj3360183.
6
The early growth response protein (EGR-1) regulates interleukin-2 transcription by synergistic interaction with the nuclear factor of activated T cells.早期生长反应蛋白（EGR-1）通过与活化T细胞核因子的协同相互作用来调节白细胞介素-2的转录。
J Biol Chem. 1998 Oct 9;273(41):26923-30. doi: 10.1074/jbc.273.41.26923.
7
Early growth response factor 1: a pleiotropic mediator of inducible gene expression.早期生长反应因子1：诱导型基因表达的多效性调节因子
J Mol Med (Berl). 1998 Aug;76(9):613-6. doi: 10.1007/s001090050258.
8
Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2.转录因子Egr-1对人纤维肉瘤细胞生长的抑制作用涉及Bcl-2的下调。
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Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants.早期生长反应因子-1（Egr-1）和特异性蛋白1（Sp1）与5-脂氧合酶启动子及其天然存在的突变体在功能上相互作用。
Am J Respir Cell Mol Biol. 1998 Aug;19(2):316-23. doi: 10.1165/ajrcmb.19.2.3154.
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Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1.应激诱导即刻早期基因egr-1涉及p38/JNK1的激活。
Oncogene. 1998 Jun 4;16(22):2915-26. doi: 10.1038/sj.onc.1201834.
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