The absorption of epsilon-(gamma-L-glutamyl)-L-lysine in different parts of the gastrointestinal tract in the rat.

A study was made on the absorption of epsilon-(yamma-L-glutamyl)-L-lysine (GL) from the small intestine and caecum of the rat. Under the experimental condition (incubation at 37 degrees for 60 min), GL was absorbed from the small intestine by an active transport mechanism and from the caecum by passive diffusion. L-lysine had no effect on the rate of absorption of GL which may suggest the existence of independent mechanisms of absorption of these two compounds in the small intestine of the rat.