Guandalini S, Dincer A P
University of Chicago, Department of Pediatrics, Illinois, USA.
Baillieres Clin Gastroenterol. 1998 Dec;12(4):697-717. doi: 10.1016/s0950-3528(98)90004-5.
Adequate nutritional intervention in diarrhoeal disease in children is crucial in obtaining optimal control of a disorder that may become life-threatening. During recent years, important advances have been made in our understanding of the pathophysiology of diarrhoeal states, in the formulation of oral rehydration solutions and in the role of micro- and macronutrients in diarrhoeal disorders. This chapter outlines some of the relevant concepts in the pathophysiology of diarrhoeal disease and provides a rationale for nutritional intervention. Guidelines for nutritional management in the settings of acute-onset diarrhoea, post-enteritis protracted diarrhoea and chronic non-specific diarrhoea are provided, mostly based on controlled clinical trials and meta-analyses of evidence-based medicine.
对儿童腹泻病进行充分的营养干预，对于实现对这种可能危及生命的疾病的最佳控制至关重要。近年来，我们在腹泻状态的病理生理学理解、口服补液溶液的配方以及微量和宏量营养素在腹泻疾病中的作用方面取得了重要进展。本章概述了腹泻病病理生理学中的一些相关概念，并为营养干预提供了理论依据。文中提供了急性发作性腹泻、肠炎后迁延性腹泻和慢性非特异性腹泻情况下的营养管理指南，这些指南大多基于循证医学的对照临床试验和荟萃分析。
