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[冬眠松鼠骨骼肌中含肌动蛋白和细肌丝蛋白的同工型状态及功能特性不存在季节性适应性变化]

[Absence of seasonal adaptive changes in the isoformic state and functional properties of actin-containing and thin filament proteins in skeletal muscles of hibernating squirrels].

作者信息

Lukoianova N A, Malyshev S L, Shpagina M D, Udal'tsov S N, Podlubnaia Z A

出版信息

Biofizika. 1998 Nov-Dec;43(6):1134-6.

PMID:10079936
Abstract

The data indicating the absence of seasonal changes in the isoform composition and functional properties of actin and thin filament associated proteins from skeletal muscles of hibernating ground squirrels were obtained. Taking into account the data obtained earlier by the authors on significant qualitative and quantitative changes in isoform composition and functional properties of the other contractile protein, myosin, it is concluded that the suppression of contractile capacity of the executive apparatus of skeletal muscles of animals upon hibernation and its repair upon arousal are determined by the above adaptive changes in myosin.

摘要

已获得数据表明,冬眠地松鼠骨骼肌中肌动蛋白和细肌丝相关蛋白的同工型组成和功能特性不存在季节性变化。考虑到作者先前获得的关于另一种收缩蛋白肌球蛋白的同工型组成和功能特性发生显著定性和定量变化的数据,得出结论:动物骨骼肌执行机构在冬眠时收缩能力的抑制及其在苏醒时的修复是由肌球蛋白的上述适应性变化决定的。

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