Ropele S, Stollberger R, Ebner F, Fazekas F
Magnetic Resonance Institute, Karl-Franzens University of Graz, Austria.
Magn Reson Med. 1999 Feb;41(2):386-91. doi: 10.1002/(sici)1522-2594(199902)41:2<386::aid-mrm24>3.0.co;2-s.
A new magnetic resonance method for T1 imaging is presented. It is based on the simultaneous acquisition of a spin echo and a phase-shifted, stimulated echo. The phase of this composite echo image is modulated heavily by the spin-lattice relaxation time T1, whereas spin density and T2 do not influence the phase information. This phase information can be assigned easily to corresponding T1 values. Although this method is sensitive to radiofrequency inhomogenities, phantom studies showed that high precision and reasonable accuracy of T1 determination can be achieved. Moreover, this method was found to be very robust, because no fitting is required. T1 imaging of the human brain was performed to confirm the in vivo utility of this method.
提出了一种用于T1成像的新磁共振方法。它基于自旋回波和相移受激回波的同时采集。该复合回波图像的相位受自旋晶格弛豫时间T1的强烈调制，而自旋密度和T2不影响相位信息。该相位信息可以很容易地与相应的T1值相关联。虽然该方法对射频不均匀性敏感，但模型研究表明，可以实现T1测定的高精度和合理准确度。此外，发现该方法非常稳健，因为不需要拟合。对人脑进行T1成像以证实该方法在体内的实用性。
