Franconi F, Seguin F, Sonier C B, Le Pape A, Akoka S
Laboratoire de Biophysique Cellulaire et RMN, Faculté de Médecine, Tours, France.
Med Phys. 1995 Nov;22(11 Pt 1):1763-9. doi: 10.1118/1.597632.
We present an imaging method to obtain a map of the spin-lattice relaxation time. Images were acquired with the same spatial resolution and in the same time as for a regular spin-echo acquisition. The sequence was based on the simultaneous acquisition of a spin echo and several stimulated echoes with the same intensity except for T1 weighting which increases with the interval between the excitation pulse and the readout pulse. T1 values obtained on phantoms were compared to those from the inversion-recovery method and show the accuracy (2%) and the precision (5%) of the method. T1 images of the brain of a healthy volunteer are presented and demonstrate the ability of the method to obtain T1 mapping in vivo in 12 min and without susceptibility artifacts. In vivo and in vitro results were compared to those obtained by a TOMROP sequence in the same acquisition time.
我们提出了一种用于获取自旋晶格弛豫时间图谱的成像方法。图像采集的空间分辨率与常规自旋回波采集相同，且采集时间也相同。该序列基于同时采集一个自旋回波和几个强度相同的受激回波，但T1加权随激发脉冲与读出脉冲之间的时间间隔增加。在体模上获得的T1值与反转恢复法得到的值进行了比较，结果显示该方法的准确性（2%）和精密度（5%）。展示了一名健康志愿者大脑的T1图像，证明了该方法能够在12分钟内且无磁化率伪影的情况下在体内获得T1图谱。将体内和体外结果与在相同采集时间内通过TOMROP序列获得的结果进行了比较。
