Verma N, Melengas S, Garap J A
Eye Clinic, Port Moresby General Hospital, Boroko, Papua New Guinea.
Aust N Z J Ophthalmol. 1999 Feb;27(1):21-5. doi: 10.1046/j.1440-1606.1999.00133.x.
PURPOSE/BACKGROUND: Penetrating keratoplasty is the logical solution for the management of corneal opacities. In situations such as in Papua New Guinea, where donor corneal tissue is scarce and corneal opacities are plenty, an alternative procedure for the management of corneal opacities in the form of ipsilateral rotational autokeratoplasty was considered.
In the present prospective study, ipsilateral rotational autokeratoplasty was performed in 17 eyes over a 2 year period in a general hospital. The patient's cornea was trephined eccentrically and the corneal opacity was dialed out of the visual axis and was replaced by clear peripheral cornea.
Most opacities were leucomata (76.4%). The average size of the opacity was 5.1 mm and the corneal button size was 7 mm.A final visual acuity of 6/18 or better was obtained in 64.7% of cases (at 12 months). No significant postoperative complications were encountered. No complex formula was needed to calculate the size of the button and, by simply adding 3 mm to the pupillary diameter in standard illumination, one could make an estimation of the graft diameter.
Rotational autokeratoplasty has a definite role in places where donor corneal tissue is scarce, in patients in whom long-term steroids are a risk or in situations where follow up of patients is difficult. Rejection is a theoretical impossibility, but late endothelial failure could occur, requiring regrafting. Rotational autokeratoplasty should be seriously considered as an alternative to conventional penetrating keratoplasty.
目的/背景:穿透性角膜移植术是治疗角膜混浊的合理方法。在巴布亚新几内亚等供体角膜组织稀缺而角膜混浊众多的情况下,人们考虑采用同侧旋转式自体角膜移植术这种替代方法来治疗角膜混浊。
在本前瞻性研究中,一家综合医院在两年时间里对17只眼睛实施了同侧旋转式自体角膜移植术。将患者的角膜偏心环切,把角膜混浊部分转出视轴,用透明的周边角膜取而代之。
大多数混浊为白斑(76.4%)。混浊的平均大小为5.1毫米,角膜植片大小为7毫米。64.7%的病例(术后12个月时)最终视力达到6/18或更好。未出现明显的术后并发症。计算植片大小无需复杂公式,在标准照明下,只需将瞳孔直径加上3毫米,就能估算出移植片直径。
旋转式自体角膜移植术在供体角膜组织稀缺的地区、长期使用类固醇有风险的患者或患者随访困难的情况下有明确作用。排斥反应理论上不可能发生,但可能出现晚期内皮功能衰竭,需要再次移植。旋转式自体角膜移植术应作为传统穿透性角膜移植术的替代方法予以认真考虑。