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氯氮䓬给药后在食物偏好测试中对熟悉食物的选择增加。

Enhanced choice of familiar food in a food preference test after chlordiazepoxide administration.

作者信息

Cooper S J, Crummy Y M

出版信息

Psychopharmacology (Berl). 1978 Sep 15;59(1):51-6. doi: 10.1007/BF00428030.

DOI:10.1007/BF00428030
PMID:100813
Abstract

Chlordiazepoxide (5.0 and 10.0 mg/kg) increased the time spent eating familiar laboratory chow, in a food-choice test in which both familiar and novel food objects were available. Chlordiazepoxide did not affect the feeding response to the novel food. Prior handling of the rats and repeat testing affected feeding responses in the test, although in ways which were different from and independent of the effect of chlordiazepoxide. Chlordiazepoxide may facilitate feeding responses by a direct enhancement of feeding motivation, and not necessarily secondarily by either a release of suppression of feeding or as attenuation of anxiety evoked by unfamiliarity.

摘要

在一项食物选择测试中,当既有熟悉的食物又有新奇的食物时,氯氮卓(5.0毫克/千克和10.0毫克/千克)增加了大鼠进食熟悉的实验室食物所花费的时间。氯氮卓不影响对新奇食物的进食反应。预先处理大鼠和重复测试会影响该测试中的进食反应,尽管其影响方式与氯氮卓的作用不同且相互独立。氯氮卓可能通过直接增强进食动机来促进进食反应,而不一定是通过解除对进食的抑制或减轻由陌生感引起的焦虑来间接促进。

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Enhanced choice of familiar food in a food preference test after chlordiazepoxide administration.氯氮䓬给药后在食物偏好测试中对熟悉食物的选择增加。
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引用本文的文献

1
Proceedings of the British Pharmacological Society. 17th-19th December, 1979: University of London (Institute of Education).英国药理学会会议记录。1979年12月17日至19日:伦敦大学(教育学院)
Br J Pharmacol. 1980 Jun;69(2):265P-346P.
2
Interactions between chlordiazepoxide and food deprivation determining choice in food-preference test [proceedings].氯氮卓与食物剥夺之间的相互作用决定食物偏好测试中的选择[会议记录]
Br J Pharmacol. 1980 Jan;68(1):157P-158P.
3
Effects of chronic chlordiazepoxide treatment on novel and familiar food preference in rats.

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Food preference following acute or chronic chlordiazepoxide administration: tolerance to an antineophobic action.急性或慢性给予氯氮卓后的食物偏好:对抗恐新行为的耐受性。
Psychopharmacology (Berl). 1981;73(1):70-4. doi: 10.1007/BF00431104.
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Effects of chlordiazepoxide and diazepam on feeding performance in a food-preference test.
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Anxiolytic actions of chlordiazepoxide determine its effects on hyponeophagia in rats.氯氮卓的抗焦虑作用决定了其对大鼠食欲减退的影响。
Psychopharmacology (Berl). 1984;82(4):343-7. doi: 10.1007/BF00427683.
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Chlordiazepoxide and preference for free food in rats.氯氮卓与大鼠对免费食物的偏好
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