Garcia E G
Am J Trop Med Hyg. 1976 Nov;25(6):914-5. doi: 10.4269/ajtmh.1976.25.914.
Single doses of oxantel given to 24 children and 37 adults with light to moderate infections of Trichuris trichiura effected cures in 20 of 26 (77%) trials with 10 mg/kg body weight, in 23 of 25 (92%) with 15 mg/kg, and in 10 of 10 trials with 20 mg/kg. In cases not cured, the egg-counts were reduced 50% to 91%. Side effects were not observed, and no drug-associated changes were detected by biochemical, hematologic, and urine examinations before and after treatment.
对24名儿童和37名轻至中度鞭虫感染的成年人单次给予奥克太尔,在26项试验中,10mg/kg体重剂量组20例(77%)治愈,15mg/kg剂量组25例中有23例(92%)治愈,20mg/kg剂量组10项试验全部治愈。未治愈的病例中,虫卵计数减少了50%至91%。未观察到副作用,治疗前后的生化、血液学和尿液检查未发现与药物相关的变化。