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多发性小汗腺汗囊肿中细胞角蛋白表达的免疫组织化学分析

Immunohistochemical analysis of cytokeratin expression in multiple eccrine hidrocystoma.

作者信息

Ohnishi T, Watanabe S

机构信息

Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.

出版信息

J Cutan Pathol. 1999 Feb;26(2):91-4. doi: 10.1111/j.1600-0560.1999.tb01808.x.

DOI:10.1111/j.1600-0560.1999.tb01808.x
PMID:10082399
Abstract

The histologic diagnosis as eccrine hidrocystoma may contain some other cysts which do not originate from the eccrine sweat glands. Some authors have suggested that true eccrine hidrocystoma does not exist. However, multiple eccrine hidrocystoma (Robinson type) is a distinct clinical entity which is characterized by multiple translucent papules around the eyelids which appear in warm weather. Cytokeratin expression in 8 cases of multiple type of unequivocal eccrine hidrocystoma was analyzed immunohistochemically. Immunoreactivities in our cases were similar to those of eccrine dermal ducts. Therefore, we confirmed that these tumors were derived from the eccrine dermal duct, not from the other appendages, and that true eccrine hidrocystoma exists.

摘要

组织学诊断为小汗腺汗囊肿可能包含一些并非起源于小汗腺的其他囊肿。一些作者认为真正的小汗腺汗囊肿并不存在。然而,多发性小汗腺汗囊肿(罗宾逊型)是一种独特的临床实体,其特征是在温暖天气时眼睑周围出现多个半透明丘疹。对8例明确的多发性小汗腺汗囊肿进行免疫组织化学分析,检测细胞角蛋白的表达。我们病例中的免疫反应性与小汗腺真皮导管的相似。因此,我们证实这些肿瘤起源于小汗腺真皮导管,而非其他附属器,且真正的小汗腺汗囊肿是存在的。

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引用本文的文献

1
[Multiple eccrine hidrocystomas on the lower forehead and nose of a 60-year-old man].[一名60岁男性前额下部和鼻部的多发性小汗腺汗囊瘤]
Hautarzt. 2017 May;68(5):393-395. doi: 10.1007/s00105-016-3900-5.
2
Apocrine hidrocystoma of the lower lip: a case report and literature review.下唇大汗腺囊瘤:一例报告并文献复习
Head Neck Pathol. 2014 Mar;8(1):117-21. doi: 10.1007/s12105-013-0451-2. Epub 2013 Jun 6.