Paavolainen P, Niemi K M
Ann Chir Gynaecol. 1976;65(5):345-51.
During the period 1968-1973 70 patients with 79 basal cell carcinomas were admitted to the Division of Plastic Surgery, Helsinki University Central Hospital. Many of these tumours were primarily treated elsewhere or sent to plastic surgery at the stage when radical surgery was no longer possible. 31 of these primary tumours developed into 70 recurrent tumours. Twelve tumours had highly destructive features. In order to evaluate the frequency of various histological growth patterns in recurring basal cell carcinoma a retrospective study was performed. It became clear that the histological growth pattern was no guide to the rate of recurrence and prognosis. The histological growth pattern of the sclerosing type was found more often in recurrent tumours, possibly a consequence of previous radiotherapy. The incidence of radiotherapy as an initial method of treatment was higher in the group of patients with primary tumours who developed recurrences. Inadequate excision margins were found more often in the same group.
1968年至1973年期间，70例患有79处基底细胞癌的患者入住赫尔辛基大学中心医院整形外科。这些肿瘤中有许多最初是在其他地方接受治疗的，或者是在无法进行根治性手术的阶段被送到整形外科的。这些原发性肿瘤中有31处发展成了70处复发性肿瘤。12处肿瘤具有高度侵袭性特征。为了评估复发性基底细胞癌中各种组织学生长模式的发生率，进行了一项回顾性研究。结果表明，组织学生长模式并不能指导复发率和预后。在复发性肿瘤中，硬化型的组织学生长模式更为常见，这可能是先前放疗的结果。在出现复发的原发性肿瘤患者组中，放疗作为初始治疗方法的发生率更高。在同一组中，切缘不充分的情况更为常见。
