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[面部皮肤癌:手术还是放疗?]

[Skin carcinoma of the face: surgery or radiotherapy?].

作者信息

Vaillant L, Goga D, Bougnoux A, Huttenberger B, Baptiste C, Lecoutre C

机构信息

Service de Dermatologie, CHU Tours.

出版信息

Rev Stomatol Chir Maxillofac. 1990;91(5):357-61.

PMID:2218385
Abstract

Surgical exeresis and radiation therapy are effective means of treatment for facial carcinomas. In some areas that are difficult to manage (nose, ears, periorbital region), the respective importance of both approaches is discussed. We report on the retrospective study of 309 patients seen after a skin carcinology consultation in which a dermatologist, a surgeon and a radiotherapist were associated. These 309 patients, with a mean age of 73 years, presented with 375 carcinomas, i.e. 246 basal-cell (BC) and 119 epidermoid (EC) carcinomas. The most frequent sites were the nose (33.8% of BC), the inner canthus (12.7% of BC), the lower lip (23.8% of EC) and the ear (15.6% of EC). Management mainly consisted of surgery (50.8%) then Curie therapy (37%). The rate of recurrence was the same (10.5%) after surgery and radiation therapy. The study of the results leads us to advocating surgery for carcinomas of the ear (due to the occurrence of radiation necrosis in every third case after radiation therapy) and Curie therapy for carcinomas of the lower lid (except the inner canthus) because of recurrence in every second case treated with surgery. We currently prefer surgery for carcinomas of the lower lip (radiodermatitis in 11.8% of cases) and Curie therapy for the nose (lower rate of recurrence than with surgery). However, in the last two cases, the proposals for treatment should be confirmed by randomized studies. Thus facial carcinomas of the skin surrounding the orifices of the face and/or those that affect patients who are difficult to treat must be seen during a skin carcinology consultation by a dermatologist, a surgeon and a radiotherapist working together.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

手术切除和放射治疗是面部癌的有效治疗手段。在一些难以处理的部位(鼻子、耳朵、眶周区域),讨论了这两种方法各自的重要性。我们报告了对309例在皮肤癌学咨询后就诊患者的回顾性研究,其中包括皮肤科医生、外科医生和放疗科医生。这309例患者平均年龄73岁,共患有375例癌症,即246例基底细胞癌(BC)和119例表皮样癌(EC)。最常见的部位是鼻子(占基底细胞癌的33.8%)、内眦(占基底细胞癌的12.7%)、下唇(占表皮样癌的23.8%)和耳朵(占表皮样癌的15.6%)。治疗主要包括手术(50.8%),然后是居里疗法(37%)。手术和放射治疗后的复发率相同(10.5%)。对结果的研究使我们主张对耳部癌症进行手术治疗(因为放射治疗后每三例中就有一例发生放射性坏死),对下睑癌症(内眦除外)进行居里疗法,因为手术治疗的每二例中就有一例复发。目前我们更倾向于对下唇癌进行手术治疗(11.8%的病例发生放射性皮炎),对鼻癌进行居里疗法(复发率低于手术治疗)。然而,在最后两例中,治疗方案应通过随机研究来证实。因此,面部孔口周围皮肤的面部癌和/或那些影响难以治疗患者的癌症,必须在皮肤癌学咨询期间由皮肤科医生、外科医生和放疗科医生共同会诊。(摘要截断于250字)

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