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强功率钕激光治疗面部癌:5 年随访数据。

Powerful neodymium laser radiation for the treatment of facial carcinoma: 5 year follow-up data.

机构信息

N.N.Petrov Research Institute of Oncology, Pesochny, St. Petersburg, 197758, Russia.

出版信息

Eur J Dermatol. 2010 Nov-Dec;20(6):738-42. doi: 10.1684/ejd.2010.1055. Epub 2010 Nov 5.

Abstract

A retrospective non-comparative follow-up study was performed to evaluate the curative efficacy of powerful neodymium laser radiation (λ = 1,060 nm) for the treatment of 2,837 patients with 3,001 histologically confirmed facial skin carcinoma lesions of stages T1-2N0M0: 2,743 primary basal cell carcinomas (BCC), 172 recurrent limited basal cell carcinomas (RLBCC), and 86 primary squamous cells carcinomas (SCC). All patients were followed-up from 5 to 11 years (mean: 8.2 years; median: 7.0 years) after treatment. The overall recurrence rate (RR) after treatment with laser radiation of facial carcinomas was 2.5% of all irradiated tumours (mean: 13.4 months; median: 11.0 months). Patients with BCC treated by radiation with the pulsed Neodymium (Nd) laser developed RR in 2.2% of cases and patients treated with the Nd:YAG laser had RR of 3.1%. Recurrences following treatment for RLBCC, and those of SCC, after irradiation with the Nd laser appeared in 4.1% and 4.6% of patients, respectively. Neodymium laser radiation is a safe and effective means of treating facial carcinomas of stages T1-2N0M0 with good cosmetic results.

摘要

一项回顾性非对照随访研究评估了强钕激光辐射(λ=1060nm)治疗 T1-2N0M0 期 2837 例 3001 例组织学证实的面部皮肤癌病变的疗效:2743 例原发性基底细胞癌(BCC)、172 例复发性局限性基底细胞癌(RLBCC)和 86 例原发性鳞状细胞癌(SCC)。所有患者在治疗后随访 5-11 年(平均 8.2 年;中位数 7.0 年)。经激光辐射治疗后,所有照射肿瘤的总复发率(RR)为 2.5%(平均 13.4 个月;中位数 11.0 个月)。用脉冲钕(Nd)激光辐射治疗的 BCC 患者的 RR 为 2.2%,用 Nd:YAG 激光治疗的患者 RR 为 3.1%。Nd 激光照射治疗的 RLBCC 和 SCC 患者的复发率分别为 4.1%和 4.6%。钕激光辐射是一种安全有效的治疗 T1-2N0M0 期面部皮肤癌的方法,具有良好的美容效果。

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