[瓦登伯革-克莱恩综合征]

[The Waardenburg-Klein syndrome].

作者信息

Ortonne J P, Perrot H, Beyvin A J, Revol L, Thivolet J

出版信息

Ann Dermatol Syphiligr (Paris). 1976;103(3):245-56.

Abstract

A case of Waardenburg-Klein syndrome associated with a Hodgkin's disease is reported in a 29 year old female. Such an association seems to be fortuitous. The authors discuss the dermatological aspects of this rare disease, particularly the disturbances of cutaneous pigmentation. Ultrastructural study of depigmented skin indicates the melanocytes are absent and precise the place of this depigmentation in the group of genetic abnormalities of skin pigmentation.

摘要

本文报道了一名29岁女性患者，患有与霍奇金病相关的瓦登伯格-克莱因综合征。这种关联似乎是偶然的。作者讨论了这种罕见疾病的皮肤病学方面，特别是皮肤色素沉着的紊乱。对色素脱失皮肤的超微结构研究表明黑素细胞缺失，并明确了这种色素脱失在皮肤色素沉着遗传异常组中的位置。