通过二倍体和四倍体胚胎之间的胚胎移植研究蝾螈（Pleurodeles waltlii）胸腺淋巴细胞的起源。
Thymic lymphocyte origin in the newt Pleurodeles waltlii studied by embryonic grafts between diploid and tetraploid embryos.
作者信息
Deparis P, Jaylet A
出版信息
Ann Immunol (Paris). 1976 Nov-Dec;127(6):827-31.
Thymic lymphocytes origin in the newt Pleurodeles waltlii was studied by embryonic grafts of the gill area between diploid and tetraploid embryos. By this way, either cell size or chromosome number are used as markers. Heterotopic transplantation of the gill area to the ventral region of a host embryo is followed by differentiation of gills and gill-associated structures including thymus. Analysis of cell size and chromosome number shows that in Pleurodeles, thymocytes do not differentiate in situ but originate from blood-borne stem cells that migrate into the thymus anlage.
通过在二倍体和四倍体胚胎之间进行鳃区的胚胎移植，研究了蝾螈（Pleurodeles waltlii）胸腺淋巴细胞的起源。通过这种方式，细胞大小或染色体数目都被用作标记。将鳃区异位移植到宿主胚胎的腹侧区域后，鳃以及包括胸腺在内的与鳃相关的结构会发生分化。对细胞大小和染色体数目的分析表明，在蝾螈中，胸腺细胞并非原位分化，而是起源于迁移到胸腺原基中的血源干细胞。
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