Lippmann H G, Graichen D, Sarembe B, Schmidt D, Löffler I, Schilling W, Preissler J
Arch Geschwulstforsch. 1976;46(7):568-609.
It is reported about the clinical testing of the "Cancer Multistep Therapy" (CMT) by M. von Ardenne (CMT Concept '74). It was made in 1974/75 on 42 tumour-patients. At first we demonstrate in this publication clinical and paraclinical findings, which may be relevant for the therapy-standard, but the results of the therapy-efficiency will be given later. On the base of findings and observations we verify a program-true employment of the CMT Concept '74 and we demonstrate the pathophysiological reaction-patterns in connection with the longterm-hyperglycemia (glucose-utilization, spontaneous hyperthermy with tachycardia, spontaneous leukocytosis with typical deviations in the hematogram). These reaction-patterns are described particularly as "general adaptation syndrome" (Selye). Further we give an assessment of compatibility, tolerableness, and practicability of the CMT.
据报道,M. 冯·阿登纳对“癌症多步疗法”(CMT,CMT概念‘74)进行了临床试验。该试验于1974年/1975年对42名肿瘤患者开展。在本出版物中,我们首先展示了可能与治疗标准相关的临床和辅助临床研究结果,但治疗效果的结果将在后面给出。基于研究结果和观察,我们验证了CMT概念‘74的程序正确应用,并展示了与长期高血糖相关的病理生理反应模式(葡萄糖利用、伴有心动过速的自发性体温过高、伴有血细胞计数典型偏差的自发性白细胞增多)。这些反应模式被特别描述为“一般适应综合征”(塞利)。此外,我们对CMT的兼容性、耐受性和实用性进行了评估。