Horinouchi T, Kano T, Fukuda Y, Kamikubo T, Hizukuri K, Tanaka H, Fukuoka Y, Kawaharada T, Tachibana H, Nakamura K
Second Department of Cardiology, Minami-Kyushu-Chuo National Hospital, Kagoshima.
J Cardiol. 1999 Feb;33(2):89-93.
A previously healthy and asymptomatic 45-year-old woman was referred for evaluation of a heart murmur and an unusual dilatation in the aortic root. Transthoracic and transesophageal echocardiography, computed tomography, magnetic resonance imaging, and cardiac catheterization revealed an aneurysm with a maximum diameter of 6.0 cm in the right sinus of Valsalva. Aortic regurgitation and stenosis at the right ventricle outflow tract were associated with the aneurysm. Surgery and histological study demonstrated that the sinus of Valsalva aneurysm was enormously dilated with idiopathic degenerative change in the aortic media. The aneurysm was tremendously large compared to any previously reported. Decrease in pressure load during diastole caused by aortic regurgitation probably resulted in the growth of this huge aneurysm without rupture.
一名45岁既往健康且无症状的女性因心脏杂音和主动脉根部异常扩张前来接受评估。经胸和经食管超声心动图、计算机断层扫描、磁共振成像及心导管检查显示,在瓦尔萨尔瓦窦右窦有一个最大直径为6.0厘米的动脉瘤。右心室流出道的主动脉瓣反流和狭窄与该动脉瘤相关。手术及组织学研究表明,瓦尔萨尔瓦窦动脉瘤因主动脉中层特发性退行性变而极度扩张。与既往报道的任何病例相比,该动脉瘤极大。主动脉瓣反流导致舒张期压力负荷降低,可能是这个巨大动脉瘤生长而未破裂的原因。