Hindermann-Fischer E, Amann F W, Jenzer H R, Blumberg A
Schweiz Med Wochenschr. 1978 Oct 21;108(42):1625-32.
Over a 2-year period uremic pericarditis was observed in 11 of 62 patients treated by chronic dialysis. The uremic state appeared to be the most important contributing factor in these patients. Chest pain, fever and a pericardial friction rub were observed in the majority of patients; the illness may however be silent. Echocardiography proved to be the single most helpful diagnostic procedure. Intensive hemodialysis, indomethacin or steroid therapy given systemically or intrapericardially are generally accepted in the management of pericarditis. Although indomethacin produced regression of the clinical symptoms in these patients, the volume of fluid within the pericardial sac diminished in 3 of 9 patients only. 6 patients were given systemic steroid treatment and this was followed by prompt resolution of the effusion. Surgery was not necessary. All patients had an uneventful recovery.
在为期2年的时间里,62例接受慢性透析治疗的患者中有11例出现了尿毒症性心包炎。尿毒症状态似乎是这些患者最重要的促成因素。大多数患者出现胸痛、发热和心包摩擦音;不过,这种疾病可能不引起任何症状。超声心动图被证明是最有用的单一诊断方法。强化血液透析、全身或心包内给予吲哚美辛或类固醇治疗,通常被认为是心包炎治疗的方法。虽然吲哚美辛使这些患者的临床症状消退,但仅9例患者中的3例心包腔内液体量减少。6例患者接受了全身类固醇治疗,随后积液迅速消退。无需进行手术。所有患者均顺利康复。