原核期胚胎移植与卵胞浆内单精子注射后体外受精-胚胎移植的比较。

Comparison of pronuclear stage embryo transfer and in vitro fertilization-embryo transfer following intracytoplasmic sperm injection.

作者信息

Kunathikom S, Suppinyopong S, Choavaratana R, Suksompong S, Julavijitpong S, Phophong P

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1999 Jan;82(1):54-8.

PMID:10087739

Abstract

To determine whether the mode of embryo transfer (PROST vs IVF) affected the outcome in intracytoplasmic sperm injection (ICSI) cycles, 237 ICSI cycles (106 PROST and 131 IVF) were analyzed. Several parameters, including patient age, duration of infertility, amounts of hMG used, number of mature eggs retrieved and injected, fertilization rate, number of embryos transferred, and clinical pregnancy rate, were compared. Most of the variable factors were not significantly different, except the mean numbers of transferred embryos which were significantly higher in the PROST group. The clinical pregnancy rate showed no statistical difference between PROST and IVF cycles (25.5 and 16.8%; p = 0.139). This study suggests that even the pregnancy rate in PROST cycles was slightly higher than IVF cycles, but there was no statistically significant difference between the two groups.

摘要

为确定胚胎移植方式（经皮输卵管内胚胎移植术[PROST]与体外受精[IVF]）是否会影响卵胞浆内单精子注射（ICSI）周期的结局，对237个ICSI周期（106个PROST周期和131个IVF周期）进行了分析。比较了多个参数，包括患者年龄、不孕持续时间、人绝经期促性腺激素（hMG）使用量、获取及注射的成熟卵子数量、受精率、移植胚胎数量和临床妊娠率。除移植胚胎的平均数量在PROST组显著更高外，大多数可变因素并无显著差异。PROST和IVF周期的临床妊娠率无统计学差异（分别为25.5%和16.8%；p = 0.139）。本研究表明，尽管PROST周期的妊娠率略高于IVF周期，但两组之间无统计学显著差异。