Khan M M, Reza H
Department of Psychiatry, Aga Khan University, Karachi.
J Pak Med Assoc. 1998 Oct;48(10):293-5.
The pattern of all index admissions for benzodiazepine self-poisoning to a university hospital in Karachi, Pakistan are described. Of the 329 medication self-poisoning cases, 84% were benzodiazepine overdoses. Diazepam was the preferred drug in 69% of these cases, with majority ingesting between 20-30 tablets of 5 mg each, 44% bought the benzodiazepine over the counter (OTC) for the purpose of overdose. The preference for benzodiazepines over analgesics (as freely available) may be related to the motives underlying parasuicide acts and their popularity as 'sleeping pills' in Pakistan. Educating the 'chemist' and limiting the number of tablets dispensed at a time are areas to consider in reducing the incidence and harmful effects of benzodiazepine overdoses in Pakistan.
本文描述了巴基斯坦卡拉奇一家大学医院所有苯二氮䓬类药物自我中毒的首次入院模式。在329例药物自我中毒病例中,84%为苯二氮䓬类药物过量。在这些病例中,69%首选地西泮,大多数人摄入20至30片每片5毫克的药物,44%为过量服用而从非处方药柜台购买苯二氮䓬类药物。相较于镇痛药(因其可随意获取),对苯二氮䓬类药物的偏好可能与准自杀行为背后的动机以及它们在巴基斯坦作为“安眠药”的流行程度有关。在巴基斯坦,对“药剂师”进行教育并限制每次配药的片数是减少苯二氮䓬类药物过量的发生率和有害影响时需要考虑的方面。