[骨膦（氯膦酸盐）两种给药方案治疗骨转移疼痛患者的随机试验]
[Randomized trial of two administration schedule of bonephos (Clodronate) in patients with painful bone metastasis].
作者信息
Moiseenko V M, Blinov N N, Semiglazov V V, Konstantinova M M, Trishkina E A
机构信息
Prof. N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF. St. Petersburg.
出版信息
Vopr Onkol. 1998;44(6):725-8.
PMID:10087976
Abstract
A randomized study of two intravenous schedules of Clodronate showed that a single 4-hour infusion of 1500 mg Clodronate proved significantly more effective than the traditional 2 hours infusion of 300 mg during 5 days. The regimen may prove preferable in therapy of patients with painful bone metastases.
摘要
一项关于氯膦酸盐两种静脉给药方案的随机研究表明，单次4小时输注1500毫克氯膦酸盐在5天内比传统的2小时输注300毫克显著更有效。该方案在治疗伴有疼痛的骨转移患者时可能更可取。
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