Poliakov P Iu, Larionova N A, Bychenkov O A, Moc'kin V G
M.F.Vladimirsky Research Clinical Institute, Ministry of Health of the RF, Moscow Region.
Vopr Onkol. 1999;45(3):311-3.
A new procedure of conservative treatment (radiation + benephos) is suggested to improve the quality of life of cancer patients with osteolytic metastases. Radiation regimen, dosage, benephos administration methods and characteristics of combined therapy are discussed. The procedure was tested in the course of the treatment of 21 breast cancer patients with osteolytic metastases. According to preliminary results, the treatment is easy to tolerate; it produced stable analgetic effect (2-9 months) in 85.7%, as compared with 42.1% in the control group.
建议采用一种新的保守治疗方法（放疗 + 氯膦酸盐）来提高骨溶解性转移癌患者的生活质量。文中讨论了放疗方案、剂量、氯膦酸盐给药方法以及联合治疗的特点。该方法在 21 例患有骨溶解性转移的乳腺癌患者的治疗过程中进行了测试。根据初步结果，该治疗易于耐受；85.7% 的患者产生了稳定的镇痛效果（2 - 9 个月），而对照组这一比例为 42.1%。
