Venco A, St John Sutton M G, Gibson D G, Brown D J
Br Heart J. 1976 Dec;38(12):1324-31. doi: 10.1136/hrt.38.12.1324.
Twenty patients were studied with simultaneous left ventricular cavity echocardiograms and apex cardiograms during the first two weeks after correction of severe aortic regurgitation. Endocardial echoes and apex cardiograms were digitized, so that left ventricular dimensions, their rates of change, and echo dimension-apex cardiogram relations could be studied. After aortic valve replacement, there was an early reduction in end-diastolic dimension, within 2 days, from 7-0 +/- 0-8 cm to 5-7 +/- 1-0 cm (P less than 0-001), while peak normalized shortening rate (peak Vcf) dropped from 1-9 +/- 0-6 to 1-4 +/- 0-6 S-1 (P less than 0-01), and remained unchanged for the remainder of the study. Immediately after operation, striking abnormalities of isovolumic contraction and, to a lesser extent, of early relaxation, could be seen, which regressed over 4 to 7 days, except in 2 patients who developed a low output state. These changes in left ventricular dimension, Vcf, and isovolumic contraction could not have been described by an single "measure" of left ventricular function.
对20例重度主动脉瓣反流矫正术后前两周的患者同时进行左心室腔超声心动图和心尖心动图检查。将心内膜回声和心尖心动图数字化，以便研究左心室尺寸、其变化率以及回声尺寸与心尖心动图的关系。主动脉瓣置换术后，舒张末期内径在2天内早期减小，从7.0±0.8 cm降至5.7±1.0 cm（P<0.001），而峰值归一化缩短率（峰值Vcf）从1.9±0.6降至1.4±0.6 S-1（P<0.01），并在研究的其余时间保持不变。术后即刻可见明显的等容收缩异常，早期舒张异常程度较轻，这些异常在4至7天内消退，但有2例患者出现低输出状态。左心室尺寸、Vcf和等容收缩的这些变化无法用单一的左心室功能“测量值”来描述。
