Moore M A, Tsuda H
Experimental Pathology and Chemotherapy Division, National Cancer Center, Research Institute, Tokyo, Japan.
Eur J Cancer Prev. 1999 Feb;8(1):7-16.
Advances in identification of the risk factors for cancer development in different organs imply more effective screening for early malignancies. The associated increase in the predictive value, as well as the introduction of procedures with high sensitivity and specificity, provide promise that early intervention will result in a marked decrease in the mortality and morbidity due to a wide range of major cancers. Furthermore, a variety of methods are now available to detect lesions at a sufficiently early stage for curative surgery to be attempted. However, for the full promise to be realized, it is of paramount importance that both physicians and the public at large are fully aware of the potential benefits.
不同器官癌症发生风险因素识别方面的进展意味着对早期恶性肿瘤进行更有效的筛查。预测价值的相应提高以及高灵敏度和特异性检测方法的引入,为早期干预将显著降低多种主要癌症导致的死亡率和发病率带来了希望。此外,现在有多种方法可在足够早期阶段检测病变,以便尝试进行根治性手术。然而,要充分实现这一前景,至关重要的是医生和广大公众都要充分认识到潜在益处。