Habbema J D
Biometrics. 1976 Dec;32(4):919-28.
The identification of the various types of the 46 chromosomes in a normal human cell is formulated as a discriminant analysis problem. Derived are expressions for posterior probabilities, and rules are given for identification where the number of chromosomes of each type is exactly known. The resulting model is applied to experimental data from chromosomes of the Denver B-group. The results using the developed model compare favorably with those of the standard discriminant analysis approach.
将正常人类细胞中46条染色体的各种类型的识别表述为一个判别分析问题。推导了后验概率的表达式,并给出了在每种类型染色体数量确切已知的情况下进行识别的规则。将所得模型应用于丹佛B组染色体的实验数据。使用所开发模型得到的结果与标准判别分析方法的结果相比更具优势。