Johnston J H, Mix L W
Br J Urol. 1976 Dec;48(6):393-8. doi: 10.1111/j.1464-410x.1976.tb06665.x.
The case is presented of a young girl with recurrent urinary tract infection and vesico-ureteric reflux who developed a small scarred kidney and subsequently, hypertension. Pathologically, the renal changes were compatible with those of an Ask-Upmark kidney. The pathogenesis of the Ask-Upmark kidney is discussed. It is postulated that the lesion is not necessarily of congenital origin but may well be related to infection and intrarenal reflux, it is concluded that long-term follow-up of a young patient with a scarred kidney is indicated.
本文介绍了一名患有复发性尿路感染和膀胱输尿管反流的年轻女孩，她出现了一个小的瘢痕肾，随后发展为高血压。病理检查显示，肾脏变化与Ask-Upmark肾相符。文中讨论了Ask-Upmark肾的发病机制。推测该病变不一定源于先天性，很可能与感染和肾内反流有关，得出结论认为应对患有瘢痕肾的年轻患者进行长期随访。
