Hacène H, Boudjellal F, Lefebvre G
Laboratoire de Microbiologie Appliquée, Université des Sciences et de la Technologie Houari-Boumediène, Alger Gare.
Microbios. 1998;96(384):103-9.
An antibiotic (AH7) produced by Streptosporangium roseum strain 214 was investigated. This compound was extracted with chloroform from the filtrate culture and purified using thin-layer chromatography and high pressure liquid chromatography procedures. The antibiotic strongly inhibited the growth of several strains of fungi and bacteria known to be plant and human pathogens. This compound differed from all other antibiotics known to be synthesized by Streptosporangium spp. Some of its chemical and physical properties resembled those of maytansines produced by Nocardia but the antibiotic AH7 has only antibacterial and antitumoral activities.
对玫瑰链孢囊菌214菌株产生的一种抗生素（AH7）进行了研究。该化合物用氯仿从滤液培养物中提取，并通过薄层色谱和高压液相色谱法进行纯化。这种抗生素强烈抑制几种已知为植物和人类病原体的真菌和细菌菌株的生长。该化合物与链孢囊菌属已知合成的所有其他抗生素不同。它的一些化学和物理性质类似于诺卡氏菌产生的美登素，但抗生素AH7仅具有抗菌和抗肿瘤活性。
