Arle J E, Alterman R L
Department of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, USA.
Med Clin North Am. 1999 Mar;83(2):483-98, vii. doi: 10.1016/s0025-7125(05)70115-2.
Surgical treatments for Parkinson's disease (PD) have again become important adjuncts of care in these patients. We have learned much from the thousands of lesions performed historically, and are now advancing the entire field of movement disorder surgery to new levels of sophistication and understanding. The last 5 years have seen more precise and reliable lesioning and the arrival of multiple sites of intervention afforded by recent developments in deep brain stimulators. Because patients typically derive significant benefit in their quality of life from these procedures, while undergoing little risk, the surgical options should be carefully considered for selected PD patients.
帕金森病（PD）的外科治疗再次成为这些患者护理的重要辅助手段。我们从历史上进行的数千例毁损手术中学到了很多，并且正在将整个运动障碍外科领域提升到新的复杂程度和认知水平。在过去5年里，出现了更精确、更可靠的毁损技术，以及深部脑刺激器的最新进展带来的多个干预靶点。由于患者通常能从这些手术中显著提高生活质量，同时风险很小，因此对于特定的帕金森病患者，应仔细考虑手术选择。
